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Protocol |
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Moleuclar size on SDS-PAGE will be shift up
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Substrate/Buffer |
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Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 0.1 M NaCl, 1mM MgCl2
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Storage |
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Store at -20 °C. Avoid freeze/thaw cycles
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References |
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Jakes, R., et. al. (1994) FEBS lett. 345, 27-32
Kim, J. (1997) Molecules and Cells 7, 78-83
Hashimoto et.al. (2001) Neuron 32, 213-223.
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Notes |
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β-synuclein (amino acids 1-134), an acidic neuronal protein of 134 amino acids, is extremely heat-resistant. β-synucelin also has a chaperone-like activity. Recently, β-synuclein has been suggested to inhibit
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