Biliverdin reductase B - Detailed product view

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Article Nr PAT-80031-1
Description Biliverdin reductase B, 1-206aa, Human, Recombinant, E.coli
Sizes 100ug
Source/Host E.coli
Species Reactivity human
MW 22, 1 kDa
Alias names   BLVRB, FLR, BVRB, SDR43U1, MGC117413 NCBI Accession No.: NP_000704.1
Purity   >95% by SDS PAGE
Sequence   MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG
ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD
LGHFMLRCLT TDEYDGHSTY PSHQYQ
Concentration   1 mg/ml
Substrate/Buffer   Liquid in 20mM Tris pH 8.5, 10% glycerol, 1mM DTT
Storage   Store at -20 °C. Avoid freeze/thaw cycles
References   L. Lee Grismer., et al. (2007). Herpetologica. 63(3):392-400
Baranano DE., et al. (2002). Proc Natl Acad Sci USA. 10; 99(25):16093-8
Notes   Biliverdin reductase B (BLVRB) is an enzyme (EC 1.3.1.24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant BLVRB protein was expressed in E.coli and purified by using conventional chromatography techniques.
Supplier   BioSite
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