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Alias names |
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BLVRB, FLR, BVRB, SDR43U1, MGC117413 NCBI Accession No.: NP_000704.1
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Sequence |
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MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ
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Substrate/Buffer |
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Liquid in 20mM Tris pH 8.5, 10% glycerol, 1mM DTT
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Storage |
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Store at -20 °C. Avoid freeze/thaw cycles
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References |
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L. Lee Grismer., et al. (2007). Herpetologica. 63(3):392-400 Baranano DE., et al. (2002). Proc Natl Acad Sci USA. 10; 99(25):16093-8
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Notes |
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Biliverdin reductase B (BLVRB) is an enzyme (EC 1.3.1.24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant BLVRB protein was expressed in E.coli and purified by using conventional chromatography techniques.
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