VAMP8 - Detailed product view

Article Nr	PAT-80229-1
Description	VAMP8, 1-76aa, Human, His tagged, Recombinant, E.coli
Sizes	100ug
Source/Host	E.coli
Species Reactivity	human
MW	10, 9 kDa

Accession No		NP_003752
Alias names		Endobrevin, EDB, VAMP 8, Vehicle associated membrane 8
Purity		>85% by SDS PAGE
Protocol		15% SDS-PAGE (3ug)
Sequence		MGSSHHHHHH SSGLVPRGSH MEEASEGGGN DRVRNLQSEV EGVKNIMTQN VERILARGEN LEHLRNKTED LEATSEHFKT TSQKVARKFW WKNVKM
Concentration		0, 25 mg/ml
Substrate/Buffer		20mM Tris pH8.0. 0.1mM PMSF, 0.2M NaCl, 50% glycerol
Storage		Store at -20 °C. Avoid freeze/thaw cycles
References		Polgár J., et al. (2002). Blood. 100(3):1081-3 REN Q., et al. (2007). Mol Biol Cell.. 18(1):24-33
Notes		Vehicle-associated membrane (VAMP8) , also known as endobrevin, is the main components of a SNARE complex involved in the docking and fusion of synaptic vesicles with the presynaptic membrane. This protein plays a role in regulated enzyme secretion in pancreatic acinar cells and is involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. It is required for dense-granule secretion in platelets. Recombinant VAMP8 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Supplier		BioSite