BAALC - Detailed product view

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Article Nr PAT-80413-1
Description Recombinant human BAALC, 1- 145 aa, His-tagged
Sizes 100ug
Source/Host E.coli
Species Reactivity human
MW 17.7 kDa (165aa)
Accession No   NP_079088
Alias names   Brain and acute leukemia, cytoplasmic isoform 1
Purity   >95% by SDS-PAGE
Sequence   MGSSHHHHHH SSGLVPRGSH MGCGGSRADA IEPRYYESWT RETESTWLTY TDSDAPPSAA APDSGPEAGG LHSGMLEDGL PSNGVPRSTA PGGIPNPEKK TNCETQCPNP QSLSSGPLTQ KQNGLQTTEA KRDAKRMPAK EVTINVTDSI QQMDRSRRIT KNCVN
Concentration   0.5 mg/ml (determined by Bradford assay)
Substrate/Buffer   Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 20% glycerol, 2mM EDTA
Storage   Can be stored at +4°C short term (1-2 week). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles
References   Tanner SM., et al. (2001) Proc Natl Acad Sci U S A. 98(24):13901-6.
Satoskar AA., et al. (2005) Gene Expr Patterns. 5(4):463-73
Contents/Specifications   Recombinant human BAALC, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
Notes   Brain and acute leukemia, cytoplasmic (BAALC) is localizes to both the membrane and the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed by hematopoetic and neural cells, BAALC interacts with CaMKIIα and is thought to play a role in synaptic function at postsynaptic lipid rafts. Overexpression of BAALC concomitant predict adverse clinical outcome and may define important risk factor in cytogenetically normal acute myeloid leukemia (AML).
Supplier   BioSite
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