BMP2 - Detailed product view

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Article Nr PAT-80238-0
Description Recombinant human BMP2, 283-396aa
Sizes 20 µg
Source/Host E.Coli
Species Reactivity human
MW 13 kDa (115aa)
Accession No   NP_001191
Alias names   Bone morphogenetic Protein 2, BMP-2A
Purity   >95% by SDS PAGE
Sequence   MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
Concentration   0, 5 mg/ml (determined by Bradford assay)
Substrate/Buffer   Liquid. In 10 mM Sodium Citrate (pH 3.5) containing 10% glycerol
Storage   Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles
References   Chen D., et al. (2004). Growth factors. 22(4):233-41
Schliephake H., et al. (2005). Clin Oral Implants Res. 17(6):666-72
Contents/Specifications   Recombinant human BMP-2 protein was expressed in E.coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer.
Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method)
Notes   BMP-2 (Bone morphogenetic protein 2) is multi-functional growth factors that belong to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility
Supplier   BioSite
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