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Alias names |
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Bone Morphogenetic protein 2, BMP-2, BMP2A
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Purity |
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>95% by SDS-PAGE gel and HPLC analyses
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Activity |
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The ED50 as determined by the cytolysis of MC3T3-E1 cells is < 50 ng/ml.
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Sequence |
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MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR.
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Substrate/Buffer |
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BMP-2 was lyophilized from a concentrated (1mg/ml) sterile solution containing 20mM NaAc pH4. It is recommended to reconstitute the lyophilized Bone Morphogenetic Protein-2 in sterile 20mM AcOH (acetic Acid) not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
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Storage |
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Upon reconstitution BMP2 should be stored at 4°C between 2-7 days and for future use below -18°C.
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Contents/Specifications |
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Bone Morphogenetic Protein-2 Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated, Polypeptide chain containing 115 amino acids and having a molecular mass of 26018 Dalton.
The BMP-2 is purified by proprietary chromatographic techniques
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Notes |
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BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein induces bone formation. BMP2 is a candidate gene for the autosomal dominant disease of fibrodysplasia (myositis) ossificans progressiva.
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