BAG1, 1- 230 aa - Detailed product view

Price: N/A - Request  Buy
Article Nr PAT-80452-1
Description Recombinant human BAG1, 1- 230 aa
Sizes 100ug
Source/Host E.coli
Species Reactivity human
MW 25.9 kDa (230aa), confirmed by MALDI-TOF
Accession No   NP_001165886
Alias names   BCL2-associated athanogene 1, HAP, RAP46
Sequence   MNRSQEVTRD EESTRSEEVT REEMAAAGLT VTVTHSNEKH DLHVTSQQGS SEPVVQDLAQ VVEEVIGVPQ SFQKLIFKGK SLKEMETPLS ALGIQDGCRV MLIGKKNSPQ EEVELKKLKH LEKSVEKIAD QLEELNKELT GIQQGFLPKD LQAEALCKLD RRVKATIEQF MKILEEIDTL ILPENFKDSR LKRKGLVKKV QAFLAECDTV EQNICQETER LQSTNFALAE
Concentration   1 mg/ml (determined by Bradford assay)
Substrate/Buffer   Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 100mM NaCl, 10% glycerol
Storage   Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles
References   Wang HG., et al. (1996) Proc Natl Acad Sci U S A. 93(14):7063-8.
Takayama S., et al. (1995) Cell. 80(2):279-84.
Notes   BCL2-associated athanogene, also known as BAG1, is a member of the Bcl-2 family of proteins that play varied stimulatory or inhibitory roles in the regulation of programmed cell death. This functions in conjunction with Bcl-2 to inhibit apoptosis. Also, BAG1 has been implicated in age related neurodegenerative diseases as Alzheimer's. It is localized to the cytosol, nucleus or both. Recombinant human BAG1 was expressed in E.coli and purified by using conventional chromatography techniques
Supplier   BioSite
Price: N/A - Request  Buy