14-3-3 tau, 1-245aa - Detailed product view

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Article Nr PAT-80005-0
Description 14-3-3 tau , 1-245aa, Human, Recombinant, E.coli
Sizes 20 µg
Source/Host E.coli
Species Reactivity human
MW 27 kDa
Accession No   NP_006817
Alias names   YWHAQ, 1C5, HS1, 14.3.3, tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein, theta polypeptide , 14.3.3 tau
Purity   >95% by SDS PAGE
Sequence   MEKTELIQKA KLAEQAERYD DMATCMKAVT EQGAELSNEE RNLLSVAYKN VVGGRRSAWR VISSIEQKTD TSDKKLQLIK DYREKVESEL RSICTTVLEL LDKYLIANAT NPESKVFYLK MKGDYFRYLA EVACGDDRKQ TIDNSQGAYQ EAFDISKKEM QPTHPIRLGL ALNFSVFYYE ILNNPELACT LAKTAFDEAI AELDTLNEDS YKDSTLIMQL LRDNLTLWTS DSAGEECDAA EGAEN
Concentration   1 mg/ml
Substrate/Buffer   In 20mM Tris pH7.5
Storage   Store at -20 °C. Avoid freeze/thaw cycles
References   Liu YC , et al. (1996) J Biol Chem; 271: 14591-5
Xiao B , et al. (1995) Nature, 376; 188-191
Notes   The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis. Recombinant human YWHAQ was expressed in E.coli and purified by using conventional chromatography techniques.
Supplier   BioSite
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