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Alias names |
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p100, TDRD11, SND1, TudorSN, staphylococcal nuclease and tudor domain containing 1
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Protocol |
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications. Determining optimal working dilutions by titration test.
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Substrate/Buffer |
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Ascitic fluid containing 0.03% sodium azide.
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Storage |
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Store at 4℃, for long term storage, store at -20℃.
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References |
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1. J Gen Virol. 2003 Sep;84(Pt 9):2317-22.
2. Biochim Biophys Acta. 2005 Jan 11;1681(2-3):126-33.
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Notes |
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SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, it functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
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