SOX2 - Detailed product view

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Article Nr AMB-7226
Description Anti-SOX2, mouse monoclonal
Sizes 0.1ml
Format unconjugated
Source/Host mouse
Immunogen Purified recombinant fragment of SOX2(aa1-170) expressed in E. Coli.
Clone 10F10C9
Isotype IgG1
Applications ELISA, WB
Species Reactivity human
MW 34.3kDa
Accession No   NP_003097
Alias names   ANOP3, MCOPS3, MGC2413, SOX2, SRY sex determining region Y-box 2
Protocol   Western Bloting: 1/500 - 1/2000. ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.
Substrate/Buffer   Ascitic fluid containing 0.03% sodium azide.
Storage   Store at 4℃, for long term storage, store at -20℃.
References   1. Exp Neurol. 2007 Apr;204(2):828-31. 2. Nature. 2008 Jan 10;451(7175):141-6.
Notes   SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP_003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Related products   1. AMB-7230, Mouse Monoclonal Antibody to LIN28
2. AMB-7246, Mouse Monoclonal Antibody to NANOG
Supplier   BioSite mAb
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