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Alias names |
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PI, A1A, AAT, PI1, A1AT, MGC9222, PRO2275, MGC23330, SERPINA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
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Protocol |
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications. Determining optimal working dilutions by titration test.
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Substrate/Buffer |
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Ascitic fluid containing 0.03% sodium azide.
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Storage |
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Store at 4℃, for long term storage, store at -20℃.
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References |
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1. J Proteome Res. 2005 Nov-Dec;4(6):2070-80.
2. Neuro Endocrinol Lett. 2008 Aug;29(4):482-4.
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Notes |
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AAT, also known as SERPINA1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.
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