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Alias names |
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AAT6, ACTSA, α-Smooth Muscle Actin
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Protocol |
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Western Bloting: 1/500 - 1/2000
Immunohistochemistry: 1/200 - 1/1000
Immunofluorescence: 1/200 - 1/1000
Flow cytometry: 1/200 - 1/400
ELISA: Propose dilution 1/10000
Not yet tested in other applications. Determining optimal working dilutions by titration test.
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Substrate/Buffer |
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Ascitic fluid containing 0.03% sodium azide.
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Storage |
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Store at 4℃, for long term storage, store at -20℃.
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References |
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1. J Hum Genet. 2009 Nov;54(11):687-8.
2. Hum Mutat. 2009 Oct;30(10):1406-11.
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Notes |
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The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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