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ESR1

Article No:
AMB-9417
Type: 
Antibodies, Primary
Research area: 
Cell Biology
Application: 
ELISA, FC, ICC, IHC, WB
Clone: 
6A6E8
Size: 
0,1 mg
Price: 

Specifications

Description: 

Mouse Monoclonal Antibody to ESR1

Isotype: 
IgG1
Substrate/Buffer: 

PBS with 0.05% sodium azide

Notes: 

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

Supplier: 
BioSite mAb

Shipping info

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