Science Hub

Molecular Biology

Welcome to Nordic BioSite's Life Science Blog. Here, we will provide commentary on current events and trends in biological sciences, interesting stories about important scientists, technical tips and suggestions, and much more. Read on and learn something new.
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CRISPR: History and Applications in Brief

 

CRISPR-Cas9 is a modern genome-editing tool that has its roots in an ancient prokaryotic immune system. Since its first adaption as a genome-editing tool in living eukaryotic cells less than a decade ago, CRISPR has undergone massive development and today it represents a rapidly growing toolbox with broad applications.

This piece gives a brief overview on the history of CRISPR and how it is used today.

Epigenetics Crash Course 3

Our Epigenetics series continues! So far in Part 1 and Part 2, we’ve introduced the field of epigenetics and the bisulfite-based approaches to studying DNA and RNA methylation. In Part 3, we look at non-bisulfite methods to study nucleic acid methylation.

Epigenetics Crash Course 2

Welcome to part 2 of our Epigenetics series. In Part 1, we gave an overview about what epigenetics is and the various types of epigenetic modifications that may occur. In this post, we will look at methods used to study DNA and RNA methylation.

Epigenetics Crash Course 1

Welcome to the 1st article in our brand new series about epigenetics.

If you are starting out in the field for the first time and want to get familiar with what epigenetics is about, what questions epigenetic studies can answer and how epigenetics is investigated then you’ve come to the right place!

In this first post, we describe what epigenetics is, how it differs to genetics, and we provide an overview of the various types of epigenetic modifications that may occur.

 

RNA Isolation in 7 Minutes – Go!

Total RNA is the starting point for a plethora of applications that can help to answer questions about the mechanisms of human and plant disease, gene regulation, embryonic development, transcriptional responses to treatments and stimuli, and more. Regardless of the application in hand – whether it be cDNA synthesis for reverse-transcription PCR, RNA-seq, northern blotting or otherwise, sufficient amounts of high-quality RNA will be a requisite.