Latest News from Epigentek

  • Quantitatively measure HAT or HDAC amounts
  • Easy ELISA kits for measuring 5-mC or 5-hmC in DNA Test
  • Quantify histone H3 or H4 methylation & acetylation.
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Measure histone acetyltransferases (HATs) or histone deacetylases (HDACs) using Epigentek’s fast and easy microplate-based kits.

Epigentek’s ready-to-use kits have the following advantages:

  • Fast & easy procedures that can be finished within 3 to 4 hours
  • No need for radioactivity, extraction, or chromatography
  • Quantitatively measure HAT or HDAC amounts
  • Flexible strip-well microplate format for manual or high throughput assays
EpiQuik HAT Activity/Inhibition Assay Kit

Catalog #: P-4003
Directly measure histone acetyltransferase (HAT) activity/inhibition a small amount of input in just 3 hours.

Epigenase HDAC Activity/Inhibition Direct Assay Kits

Catalog #: P-4034 & P-4035
Directly measure total histone deacetylase (HDAC) activity/inhibition from a small amount of input in just 3 1/2 hours.

EpiQuik HDAC1 -7 Assay Kits
See our complete line of ELISA-like kits to quantitatively measure total amount of individual HDAC proteins (1-11) using nuclear extracts or purified enzymes from various mammalian cells/tissues within 4 hours.  View kits
Nuclear Extraction Kits
Reliably and conveniently isolate nuclear proteins from cells or tissues in just one hour. The extracts can be used in EpiGentek’s DNMT, HMT, histone demethylases, HDAC, and HAT kits or in a variety of applications.  View kits

 


Fast, Simple, Accurate Results & Peace of Mind!

Quickly measure global DNA methylation or hydroxymethylation in just 2 hours using Epigentek’s MethylFlash ELISA Easy Kits.

Advantages Of the MethylFlash Global DNA 5-mC & 5-hmC ELISA Easy Kits:

  • Fast – Finish in only 2 hours
  • Robust – Greater “signal window” with reduced replicate variation
  • Convenient – No need for DNA denaturation and plate blocking steps
  • Sensitive – Low detection limit from just 100 ng of input DNA
  • Specific – No cross-reactivity to unmethylated or modified cytosines
  • Universal – Detects single or double-stranded DNA from any species
  • Accurate – Highly comparable to HPLC-MS analysis
  • Flexible – Perform manual or high throughput analysis

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Need Just The 5-mC & 5-hmC Antibodies?

Get the same high-quality antibodies Epigentek use in their MethylFlash kits.

5-mC Monoclonal Antibody

Catalog #: P-1014

Validated Applications: DB, ELISA, IF, IHC, IP, MeDIP
Clone: 33D3
Isotype: IgG1
Host: Mouse
Purification: Affinity Purified

5-hmC Monoclonal Antibody

Catalog #: A-1018

Validated Applications: DB, ELISA, IF, IHC, hMeDIP
Clone: HMC / 4D9
Isotype: IgG1
Host: Mouse
Purification: Affinity Purified

 


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Evaluate histone post-translational modifications (PTMs) such as methylation or acetylation using any one of our site-specific H3 or H4 ELISA-like quantification assays.

 

The advantages of Epigentek’s histone quantification kits include:

  • Fast & easy procedure that can be finished within 2 hours and 30 minutes
  • Low detection limits with a range from 5 ng to 5 µg/well of histone extracts
  • Flexible strip-well microplate format for manual or high throughput assays
Histone H3 & H4 Methylation Quantification Kits

Our kits cover the most widely studied mono-, di- and tri-methylation sites: H3K4, H3K9, H3K27, H4K20, H3K36, H3K79, H4K20, H3R8, and H4R3.

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Histone H3 and H4 Acetylation Quantification Kits

Our kits cover the most widely studied acetylation sites: H3K9, H3K14, H3K18, H3K27, H3K36, H3K56, H4K5, H4K8, H4K12, H4K16, and H4K16.

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ELISA Kits for Measuring Histone H3 Citrullination
Histone citrullination in epigenetic regulation is a potential biomarker for certain autoimmune diseases. For researchers looking to study this epigenetic modification, we offer the EpiQuik Histone H3 Citrullination ELISA Kit and EpiQuik Circulating Histone H3 Citrullination ELISA Kit – two convenient and fast methods for measuring global histone H3 citrullination (at arginines R2, R8, R17) respectively from histone extracts or plasma/serum.

  • P-3095 measures from histone extracts
  • P-3097 measures from plasma/serum

 

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