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MBL: MHC Class I & II Tetramer, MHC Monomers, CD1d Tetramers

news November 24 2017

TCRs recognize and bind to complexes composed of MHC molecules and specific peptides expressed on the surface of antigen-presenting cells. We have tetramerized and biotinylated with streptavidin to maintain stable binding to multiple TCR, enabling MHC/peptide tetramers to be used as detection tools. Phycoerythrin (PE), allophycocyanin (APC), or Brilliant Violet™ 421 (BV421) fluorophores are available for detection of antigen-specific T cells by flow cytometry or fluorescence microscopy.

• MBL tetramers offer Superior Specificity with α3 Mutation

• Class I and Class II Available

• PE, APC and BV421 Conjugates Available

• Over 60 alleles available

• Custom Services Available

Learn about the types of MHC Molecules

Tetramers Monomers Class I Class II

CD1d Non-Classical Immune Monitoring FAQ Tetramer Citations

Superior Specificity with Patented α3 Mutation

Impact of α3 Mutation

See All Tetramer Products See All Monomer Product