MBL: MHC Class I & II Tetramer, MHC Monomers, CD1d Tetramers

news November 24 2017

TCRs recognize and bind to complexes composed of MHC molecules and specific peptides expressed on the surface of antigen-presenting cells.  We have tetramerized and biotinylated with streptavidin to maintain stable binding to multiple TCR, enabling MHC/peptide tetramers to be used as detection tools.  Phycoerythrin (PE), allophycocyanin (APC), or Brilliant Violet™ 421 (BV421) fluorophores are available for detection of antigen-specific T cells by flow cytometry or fluorescence microscopy.

• MBL tetramers offer Superior Specificity with α3 Mutation

• Class I and Class II Available

• PE, APC and BV421 Conjugates Available

Over 60 alleles available

Custom Services Available

Learn about the types of MHC Molecules

Tetramers     Monomers      Class I      Class II

CD1d    Non-Classical   Immune Monitoring FAQ   Tetramer Citations 


Superior Specificity with Patented α3 Mutation

Impact of α3 Mutation 

See All Tetramer Products     See All Monomer Product

Learn more about QuickSwitch™ Custom Tetramer Kits


See Flow Cytometry Products 

Find important tetramer documents below:

Tetramer Allele List    Custom Order Form   Request Tetramer Staining Guide