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TCRs recognize and bind to complexes composed of MHC molecules and specific peptides expressed on the surface of antigen-presenting cells. We have tetramerized and biotinylated with streptavidin to maintain stable binding to multiple TCR, enabling MHC/peptide tetramers to be used as detection tools. Phycoerythrin (PE), allophycocyanin (APC), or Brilliant Violet™ 421 (BV421) fluorophores are available for detection of antigen-specific T cells by flow cytometry or fluorescence microscopy. • MBL tetramers offer Superior Specificity with α3 Mutation • Class I and Class II Available |
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Learn about the types of MHC Molecules Tetramers Monomers Class I Class II CD1d Non-Classical Immune Monitoring FAQ Tetramer Citations
Superior Specificity with Patented α3 Mutation Impact of α3 Mutation |
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Learn more about QuickSwitch™ Custom Tetramer Kits
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Find important tetramer documents below:
Tetramer Allele List Custom Order Form Request Tetramer Staining Guide