New COVID-19 Research Assays

SARS-CoV-2 IgG (Spike RBD) Serological ELISA Kit

AdipoGen Life Scienceshas developed a sensitive and specific SARS-CoV-2 (Spike RBD) IgG Serological ELISA Kit that can be used for the qualitative measurement of human Immunoglobulin G (IgG) against SARS-CoV-2 Spike (Receptor Binding Domain) protein in serum and plasma samples.

Positive Control Plate
Included in this assay kit and unique to the market for SARS-CoV-2 IgG assays, is a second plate (antigen non-coated Background Plate or False Positive Control Plate) to determine the sample specific background and to measure the amount of IgG antibodies non-specifically bound to the well. To measure presence of anti-SARS-CoV-2 human IgG antibodies in serum or plasma, net sample optical densities (Net ODs) are calculated by subtracting each sample Background Plate OD from the Spike (SARS-CoV-2) Antigen Plate (Spike Plate) OD.

Dry Blood Samples
The Assay Kit can also be used with Dry Blood Samples, which is an inexpensive and easy alternative collecting blood.

SARS-CoV-2 Neutralizing Antibodies Detection Kit

AdipoGen Life Sciences has developed a sensitive, specific and fast SARS-CoV-2 Neutralizing Antibodies Detection Kit that can be used to detect the presence of neutralizing antibodies against SARS-CoV-2 in serum/plasma in about 2 hours independently of species and isotypes.

The SARS-CoV-2 Neutralizing Antibodies Detection Kit contains key reagents required to test the presence of functional neutralizing antibodies against SARS-CoV-2 present in the serum or plasma. It is an easy, safe, fast and scalablealternative to the classical neutralization assays using Vero E6 cells, such as virus neutralization test (VNT) and pseudo-virus neutralization test (pVNT) and does not need to follow biosafety requirements.

Useful Tool for SARS-CoV-2 Vaccine and Therapeutic Development
This kit is administrable in vaccine and therapeutic development as it is suitable for all antibody isotypes and can be used to determine neutralizing antibodies in human and animal models. The kit is useful in current COVID-19 investigations of sero-prevalence, assessment of immune response, herd immunity, longevity of protective immunity, efficacy of different vaccine candidates as well as tracking infections in animals.

To Confirm & Characterize further SARS-CoV-2 Serological Assay Results
This Neutralizing Antibody Detection Kit is ideal to further characterize the positive anti-SARS-CoV-2 IgG antibodies, detected with the SARS-CoV-2 IgG (Spike RBD) Serological ELISA Kit.

SARS-CoV-2 Inhibitor Screening Kit

AdipoGen Life Sciences’ SARS-CoV-2 Inhibitor Screening Kit has been developed as a High Throughput Screening (HTS) detection assay for the determination of SARS-CoV-2 blocking compounds.

The SARS-CoV-2 Inhibitor Screening Kit contains key reagents required to facilitate identification of SARS-CoV-2 inhibitors. This inhibitor screen is based on a colorimetric ELISA kit, which measures the binding of the RBD of the Spike S protein from SARS-CoV-2 to its human receptor ACE2.

ACE2 (human) ELISA Kit

AdipoGen Life Scienceshas developed a sensitive and specific colorimetric sandwich ACE2 (human) ELISA Kit that can be used for the in vitro quantitative determination of soluble human ACE2 in cell culture supernatants, serum, plasma and urine.

ACE2 functions as the entry receptor of the new SARS-CoV-2 coronavirus that is the cause of the new disease COVID-19. Strong binding of the Spike protein of SARS-CoV-2 to ACE2, along with proteolytic cleavage of ACE2 by transmembrane serine protease 2 (TMPRSS2), facilitates entry of the virus into cells, viral replication and cell-to-cell transmission. Soluble ACE2 may act as a competitive interceptor of SARS-CoV-2 and other coronaviruses by preventing binding of the viral particle to the surface-bound, full-length ACE2. A reliable ELISA Kit to determine circulating soluble human ACE2. Useful for testing developmental therapeutics.