Trusted Inflammasome Reagents
- Inflammasome complexes (NLRPs, RIG-I like, AIM2) and other sensors such as ZBP1 detect dangers (infection, wound, rupture of homeostasis) in the cytoplasm.
- Inflammasomes activate caspase-1, which causes cleavage/maturation of IL-1β, IL-18 and Gasdermin D and leads to inflammation and later to pyroptosis.
- AdipoGen’s “Standard” antibodies are in-house validated, cited in hundreds of publications, and used worldwide used by the experts in inflammasome and gasdermin research.
Gold Standard Inflammasome Antibodies
|anti-Caspase-1 (p20) (mouse), mAb (Casper-1)||AG-20B-0042|
|anti-Caspase-1 (p10) (mouse), mAb (Casper-2)||AG-20B-0044|
|anti-Caspase-1 (p20) (human), mAb (Bally-1)||AG-20B-0048|
|anti-NLRP3/NALP3, mAb (Cryo-2)||AG-20B-0014|
|anti-Asc, pAb (AL177)||AG-25B-0006|
New Gasdermin C-terminus Antibody
|anti-Gasdermin D (mouse), pAb (IN110)||AG-25B-0036|
ZBP1 – A New Influenza Virus Sensor
|anti-ZBP1, mAb (Zippy-1)||AG-20B-0010|