Trusted Inflammasome Reagents

  • Inflammasome complexes (NLRPs, RIG-I like, AIM2) and other sensors such as ZBP1 detect dangers (infection, wound, rupture of homeostasis) in the cytoplasm.
  • Inflammasomes activate caspase-1, which causes cleavage/maturation of IL-1β, IL-18 and Gasdermin D and leads to inflammation and later to pyroptosis.
  • AdipoGen’s “Standard” antibodies are in-house validated, cited in hundreds of publications, and used worldwide used by the experts in inflammasome and gasdermin research.

Gold Standard Inflammasome Antibodies

anti-Caspase-1 (p20) (mouse), mAb (Casper-1) AG-20B-0042
anti-Caspase-1 (p10) (mouse), mAb (Casper-2) AG-20B-0044
anti-Caspase-1 (p20) (human), mAb (Bally-1) AG-20B-0048
anti-NLRP3/NALP3, mAb (Cryo-2) AG-20B-0014
anti-Asc, pAb (AL177) AG-25B-0006

New Gasdermin C-terminus Antibody

anti-Gasdermin D (mouse), pAb (IN110) AG-25B-0036

ZBP1 – A New Influenza Virus Sensor

anti-ZBP1, mAb (Zippy-1) AG-20B-0010