New Optibodies are launched!

 


Picture. F8 25.0x leiomyoma

Optibodies Factor 8

Description: Anti-Factor 8, rabbit monoclonal - Optibodies

F8 is coagulation factor VIII acting as procoagulant component. F8 participates 
in the intrinsic pathway of blood coagulation. F8 is a product of the von Willebrand 
factor gene, and it is expressed in endothelial cells, megakaryocytes and 
thrombocytes. However, endothelial cells of large blood vessels, liver sinusoids 
and lymphatics are often F8 negative. Defects in F8 gene results in hemophilia A, 
a common recessive X-linked coagulation disorder. This antibody is useful for 
detection of the vascular neoplasms for example with CD31 and CD34.

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Picture. CK7 BS28, Pancreas, 20.0x

Optibodies Cytokeration 7

Description: Anti-Cytokeratin 7, mouse monoclonal - Optibodies

Cytokeratin 7 (CK7) is a protein that in humans is encoded by the KRT7 gene. 
CK7 is a member of the keratin family and it is specifically expressed in the 
simple epithelia lining the cavities of the internal organs and in the gland ducts. 
The type II cytokeratins consist of basic or neutral proteins which are arranged in 
pairs of heterotypic keratin chains co-expressed during differentiation of simple 
and stratified epithelial tissues. IHC staining of cytokeratin 7 is useful for 
carcinoma diagnostic especially for differential diagnosis of urothelial, lung,
breast carcinomas to colorectal or prostate carcinomas. CK7 is especially marker 
of lung adenocarcinoma. Pancreas is the good tissue control for CK7.

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