Article No
10-10013-100
c-MYC
Monoclonal Antibody to c-MYC (Clone:9 E 10)
Antibodies Primary
Specifications
| Application | WB |
| Article No | 10-10013-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 9 E 10 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to c-MYC (Clone:9 E 10) |
| Supplier | Abeomics |
| Entrez Gene ID | 4609 |
| Gene Symbol | MYC |
| Immunogen | A synthetic peptide corresponding to amino acids 408-432 (AEEQKLISEEDLLRKRREQLKHKLE) of human c-Myc was used as the immunogen for this antibody. |
| Isotype | IgG1 k |
| Keywords | Tag Antibodies, MYC, 4609, P01106, MYC, BHLHE39, 9 E 10, Monoclonal Antibody to c-Myc(Clone :9 E 10), Anti c-Myc Antibody, c-Myc Antibody |
| Notes | c-Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The Myc protein activates transcription as part of a heteromeric complex with Max. Myc protein represses the expression of Ferritin-H, which sequesters intracellular iron, and stimulates the expression of IRP2 (Iron Regulatory Protein-2), which increases the intracellular iron pool. Myc induces transcription of the E2F1, E2F2 and E2F3 genes. Myc-induced S phase and apoptosis requires distinct E2F activities. The induction of specific E2F activities is an essential component in the Myc pathways that control cell proliferation and cell fate decisions. |
| Alias Names | MYC||BHLHE39 |
| Product Type | Antibodies Primary |
| Protocol | Western blot analysis: 2-4 µg/ml |
| Purification | Protein G Purified |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | P01106 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
