Article No
10-1058-100
14-3-3 Theta
Monoclonal Antibody to 14-3-3 Theta (Clone: ABM52H6)
Antibodies Primary
Specifications
| Application | WB |
| Article No | 10-1058-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ABM52H6 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to 14-3-3 Theta (Clone: ABM52H6) |
| Supplier | Abeomics |
| Entrez Gene ID | 22630 |
| Gene Symbol | Ywhaq |
| Immunogen | Full length recombinant protein of 14-3-3 Theta was used as the immunogen for this antibody. |
| Isotype | IgG2a k |
| Keywords | Apoptosis, YWHAQ, 14-3-3 protein tau 14-3-3 protein theta, ABM52H6, Monoclonal Antibody to 14-3-3 Theta(Clone :ABM52H6), Anti 14-3-3 Theta Antibody, 14-3-3 Theta Antibody |
| Notes | 14-3-3 Theta, a member of 14-3-3 family, is an adapter protein that plays an important role in a wide range of vital regulatory processes, including signal transduction, apoptosis, cell cycle progression and DNA replication. Humans have seven 14-3-3 isoforms (beta, gamma, epsilon, eta, sigma, theta and zeta) that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes. 14-3-3 Theta binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif, resulting in the modulation of the activity of the binding partner except PDPK1, whose kinase activity is negatively regulated. Previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development of various cancers. In lung cancer biopsies, 14-3-3 Theta is found to be present in abundance. |
| Alias Names | 14-3-3 protein tau |
| Product Type | Antibodies Primary |
| Protocol | WB: 2-4 µg/ml |
| Purification | Protein G Purified |
| Research area | Cell Death |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | P68254 |
| Product Page Updated | 2024-04-03T14:02:41.041Z |
