14-3-3 Zeta

14-3-3 Zeta

Article No 11-1017-100
Product Type Antibodies Primary
Research Area Cell Death
Application WB
Format Purified
Size 100 µg

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Specifications

Country Availability SE, FI, DK, NO, IS, EE, LV, LT
Clone Type polyclonal
Data Sheet Link https://www.abeomics.com/download_pdf.php?pID=116263
Description Polyclonal Antibody to 14-3-3 Zeta
Supplier Abeomics
Immunogen A partial length recombinant 14-3-3 Zeta protein (amino acids 30-245) was used as the immunogen for this antibody.
Isotype IgG
Notes 14-3-3zeta is a central cellular hub protein regulating multiple signaling pathways involved in cancer development, progression and therapeutic resistance. It is linked to endoplasmic reticulum (ER) function in neurons, with reduced levels provoking ER stress and increasing vulnerability to excitotoxic injury. It is up-regulated in malignancy, which suggests its potential as a putative drug target for the treatment of colorectal cancer and tumorgenesis in pancreas,EOC (epithelial ovarian cancer).
Alias Names YWHAZ
Protocol Western blot analysis: 1-2 µg/ml
Purification Protein A Chromatography
Size 100
Size Unit µg
Source / Host rabbit
Species Reactivity human
Storage Store the antibody at 4⁰C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
Substrate / Buffer 100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
UniProt Number P63104
Product Page Updated 2019-01-07T14:41:25.134Z

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Source/Host:

rabbit rabbit

Species reactivity:

human human

Product insert:

Product data sheet

Datasheet

Suggested protocols:

Western Blot

Western Blot