Chemicals & Biochemicals

(+)-Aphidicolin

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(+)-Aphidicolin

Article No

154-14007-1

Size

1 mg

Shipping Information

-20

Documentation

Specifications

CAS No 38966-21-1
Additional Information A natural tetracyclic diterpene with antiviral activity against herpes simplex; a cell-permeable, reversible inhibitor of DNA replication in eukaryotic cells, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels.
Article No 154-14007-1
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, RU
Description (+)-Aphidicolin
Supplier Cayman Chemical
Notes (+)-Aphidicolin is a natural tetracyclic diterpene first isolated from the fungus C. aphidicola and shown to have antiviral activity against herpes simplex.{22496} In eukaryotic cells, it is a cell-permeable, reversible inhibitor of DNA replication, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels.{22501,22499,22497} Aphidicolin can be used, at 3 μM, to arrest cells in G1/S phase or to increase gene amplification frequency.{22498,22502}
Alias Names ICI 69653|NSC 234714
Product Type Chemicals & Biochemicals
Purity ≥98%
Shipping Information -20
Size 1 mg
Storage -20
Substrate / Buffer A solid
Product Page Updated 2021-02-17T10:48:22.248Z

Shipping info

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