Proteins & Peptides

SARS-CoV-2 Surface Glycoprotein Receptor Binding Domain (rabbit IgG1 Fc-tagged)

SARS-CoV-2 Surface Glycoprotein Receptor Binding Domain (rabbit IgG1 Fc-tagged)

Article No



100 µg

Shipping Information




Additional Information Source: Active recombinant C-terminal rabbit IgG1 Fc-tagged SARS-CoV-2 surface glycoprotein receptor binding domain expressed in HEK293 cells • Amino acids: 319-541 • MW: 50.3 kDa
Article No 154-30590
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, RU
Description SARS-CoV-2 Surface Glycoprotein Receptor Binding Domain (rabbit IgG1 Fc-tagged)
Supplier Cayman Chemical
Notes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surface glycoprotein, also known as the spike glycoprotein, is a viral structural protein encoded by the S gene in SARS-CoV-2 RNA.{53462} SARS-CoV-2 is a member of the Betacoronavirus genus of viruses and has 88% sequence identity with two bat-derived SARS-like CoVs.{53459} The SARS-CoV-2 genome contains approximately 30 kilobases that encode four structural proteins: spike, envelope, membrane, and nucleocapsid.{53462,49555} The spike protein of SARS-CoV-2 and the related viruses SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV) is a transmembrane glycoprotein that assembles into homotrimers on the virus surface and is comprised of an N-terminal S1 subunit, which contains the receptor binding domain (RBD), and a C-terminal S2 subunit, which facilitates fusion between viral and host cell membranes.{46767,46768,49561} The 193-amino acid RBD of the SARS-CoV spike protein is a target for neutralizing antibodies.{46768,49525} The SARS-CoV-2 RBD, which spans amino acid residues 329 to 521, is 73% identical to that of SARS-CoV and can bind to human angiotensin-converting enzyme 2 (ACE2), which is the host cell surface receptor for both SARS-CoV and SARS-CoV-2.{46767,49561,49525} SARS-CoV-2 is the causative agent of the COVID-19 respiratory illness characterized by fever, cough, and shortness of breath that can progress to pneumonia and potentially death in high-risk populations.{53461} Cayman’s SARS-CoV-2 Surface Glycoprotein Receptor Binding Domain (rabbit IgG1 Fc-tagged) protein can used for ELISA, surface plasmon resonance (SPR), and Western blot (WB) applications.
Alias Names S1 RBD|SARS-CoV-2 Spike Receptor Binding Domain|Spike S1 RBD
Product Type Proteins & Peptides
Purity ≥85%
Shipping Information -80
Size 100 µg
Storage -80
Substrate / Buffer PBS, pH 7.4, with 5% mannitol, 5% trehalose, 0.01% Tween 20, and 10% glycerol
Product Page Updated 2021-02-17T10:48:22.248Z

Shipping info

The delivery time for this item is approximately 8-10 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.