Article No
155-36-075
Specifications
| NCBI Number | 8074 |
| Accession Number | 10190674 |
| Application | ELISA, IHC, WB |
| Article No | 155-36-075 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | FG322-3 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | FGF-23 Antibody [FG322-3] |
| Supplier | ProSci |
| Entrez Gene ID | 8074 |
| Format | Liquid |
| Gene Symbol | FGF23 |
| Immunogen | Recombinant human FGF-23. |
| Isotype | IgG1 k |
| Notes | FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC). |
| Alias Names | Fibroblast Growth Factor 23; Tumor-derived Hypophosphatemia-inducing Factor |
| Previous Article No | 155-36-075-100 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: (direct and indirect: 1:2,000-1:5,000). Immunohistochemistry: (paraffin sections (1:100-1:500)). Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application. |
| Research area | Metabolism |
| Shipping Information | BLUE ICE |
| Size | 100 ug |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | -20°C |
| Substrate / Buffer | Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives. |
| UniProt Number | Q9GZV9 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
