Article No
155-40-264-0.002
IL-19 Recombinant Protein
IL-19 Recombinant Protein
Proteins & Peptides
Specifications
| NCBI Number | 29949 |
| Accession Number | NP_037503.2 |
| Article No | 155-40-264-0.002 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Description | IL-19 Recombinant Protein |
| Supplier | ProSci |
| Entrez Gene ID | 29949 |
| Format | Lyophilized |
| Gene Symbol | IL19 |
| Notes | IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-α and induces apoptosis through TNF-α. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant Human IL-19 is a 35.8 kDa homodimer of two 154 amino acid chains. In solution IL-19 exists predominantly as a non-disulfide-linked dimer. |
| Alias Names | MDA1, NG.1, ZMDA1, IL-10C, Interleukin-19, Melanoma differentiation-associated protein-like protein, IL-19 |
| Product Type | Proteins & Peptides |
| Purity | >98% |
| Research area | Cell Signaling |
| Sequence | MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MSSA |
| Shipping Information | RT |
| Size | 0.002mg |
| Storage | The lyophilized IL-19 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-19 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IL-19 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
| Technical Specifications | Biological activity was determined by its ability to activate STAT following receptor - ligand interaction. |
| UniProt Number | Q9UHD0 |
| Product Page Updated | 2024-01-03T13:15:21.507Z |
