Article No
155-50-265
Choline Acetyltransferase
Choline Acetyltransferase Antibody
Antibodies Primary
Specifications
| MW | 70 |
| NCBI Number | 1103 |
| Accession Number | P28329 |
| Application | IHC, WB |
| Article No | 155-50-265 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | Choline Acetyltransferase Antibody |
| Supplier | ProSci |
| Entrez Gene ID | 1103 |
| Format | Liquid |
| Gene Symbol | CHAT |
| Immunogen | Native choline acetyltransferase purified from human placenta. |
| Notes | Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999). |
| Alias Names | CMS1A, CMS1A2, CHOACTASE, CHOACTase |
| Previous Article No | 155-50-265-0.1 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Neuroscience |
| Shipping Information | BLUE ICE |
| Size | 0.1 mL |
| Source / Host | goat |
| Species Reactivity | chicken, goat, human, mouse, rat |
| Storage | Choline Acetyltransferase antibody can be stored at -20°C and is stable at -20°C for at least 1 year. |
| Substrate / Buffer | 100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol. |
| UniProt Number | P28329 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
