Article No
155-50-268
Glial Fibrillary Acidic Protein
Glial Fibrillary Acidic Protein Antibody
Antibodies Primary
Specifications
| MW | 50 |
| NCBI Number | 281189 |
| Accession Number | Q28115 |
| Application | IHC, WB |
| Article No | 155-50-268 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | Glial Fibrillary Acidic Protein Antibody |
| Supplier | ProSci |
| Entrez Gene ID | 281189 |
| Format | Liquid |
| Gene Symbol | GFAP |
| Immunogen | Recombinant and purified bovine GFAP. |
| Notes | Glial Fibrillary Acidic Protein (GFAP) was discovered by Amico Bignami and co-workers as a major fibrous protein of multiple sclerosis plaques. It was subsequently found to be a member of the 10 nm or intermediate filament (IF) family, specifically the IF family Class III, which also includes peripherin, desmin and vimentin. GFAP is strongly and specifically expressed in astrocytes and certain other astroglia in the CNS, in satellite cells, peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In many damage and disease states GFAP expression is heavily upregulated in astrocytes. In addition, neural stem cells frequently strongly express GFAP. Point mutations in the protein coding region of the GFAP gene lead to Alexander disease which is characterized by the presence of abnormal astrocytes containing GFAP protein aggregates known as Rosenthal fibers. |
| Alias Names | GFAP |
| Previous Article No | 155-50-268-0.1 |
| Product Type | Antibodies Primary |
| Purification | Total IgY fraction |
| Research area | Neuroscience |
| Shipping Information | BLUE ICE |
| Size | 0.1 mL |
| Source / Host | chicken |
| Species Reactivity | human, mouse, rat |
| Storage | Glial Fibrillary Acidic Protein antibody can be stored at -20°C and is stable at -20°C for at least 1 year. |
| UniProt Number | Q28115 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
