Article No
155-76-019
NCBI Number | 958 |
Application | FA, FC |
Article No | 155-76-019 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 5C3 |
Clone Type | monoclonal |
Concentration | batch dependent |
Conjugation | Unconjugated |
Description | CD40 Antibody [5C3] |
Supplier | ProSci |
Entrez Gene ID | 958 |
Format | Liquid |
Gene Symbol | CD40 |
Isotype | IgG1 k |
Notes | The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation. |
Alias Names | p50, Bp50, CDW40, TNFRSF5, CD40 |
Previous Article No | 155-76-019-0.05 |
Product Type | Antibodies Primary |
Purification | Affinity Purified |
Research area | Immunology |
Shipping Information | BLUE ICE |
Size | 0.05 mg |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
Substrate / Buffer | Phosphate-buffered aqueous solution, ph7.2. |
UniProt Number | P25942 |
Product Page Updated | 2024-01-03T13:34:25.701Z |