Article No
155-76-032
NCBI Number | 21948 |
Application | FA, FC |
Article No | 155-76-032 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | FR70 |
Clone Type | monoclonal |
Concentration | batch dependent |
Conjugation | Unconjugated |
Description | CD70 Antibody [FR70] |
Supplier | ProSci |
Entrez Gene ID | 21948 |
Format | Liquid |
Gene Symbol | Cd70 |
Isotype | IgG2b k |
Notes | The FR70 monoclonal antibody specifically binds to mouse CD70, a 30-33 kDA type II transmembrane protein and member of the TNF superfamily. CD70 is the ligand for CD27 and is expressed on dendritic cells, activated B cell, and a subset of activated T cells at lower levels. Its main role is in regulating B cell activation and immunoglobulin synthesis. CD70 expressing cells are able to co-stimulate T cell proliferation and upregulate cytokine production. The FR70 antibody is reported to block the binding of CD70 to CD27. |
Alias Names | Cd27l, CD27LG, Tnfsf7, Cd70 |
Previous Article No | 155-76-032-0.05 |
Product Type | Antibodies Primary |
Purification | Affinity Purified |
Research Area | Immunology |
Shipping Information | BLUE ICE |
Size | 0.05 mg |
Source / Host | rat |
Species Reactivity | mouse |
Storage | 4°C |
Substrate / Buffer | Phosphate-buffered aqueous solution, ph7.2. |
UniProt Number | O55237 |
Product Page Updated | 2024-01-03T13:34:25.701Z |