Article No
155-76-130
CD11b
CD11b Antibody [M1/70] (PerCP-Cy5.5)
Antibodies Primary
Specifications
| NCBI Number | 3684 |
| Application | FC |
| Article No | 155-76-130 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | M1/70 |
| Clone Type | monoclonal |
| Concentration | batch dependent |
| Conjugation | PerCP/Cy5.5 |
| Description | CD11b Antibody [M1/70] (PerCP-Cy5.5) |
| Supplier | ProSci |
| Entrez Gene ID | 3684 |
| Format | Liquid |
| Gene Symbol | ITGAM |
| Isotype | IgG2b k |
| Notes | The M1/70 monoclonal antibody specifically reacts with the 170 kDa alphaM integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18). Mac-1 binds to C3bi, CD54 (ICAM-1), and fibrinogen, and it is expressed by granulocytes, macrophages, NK cells, myeloid-derived dendritic cells, microglia, activated lymphocytes, and mouse B-1 cells. The expression is up-regulated on activated neutrophils at the same time that L-selectin is shed from the cell surface. The M1/70 antibody is used for the detection of monocytes, granulocytes, and a subset of natural killer cells in human peripheral blood.M1/70 blocks C3bi binding and cell adherence, but not cell-mediated lysis and it cross-reacts with human CD11b. |
| Alias Names | CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6, ITGAM |
| Previous Article No | 155-76-130-0.1 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | human, mouse |
| Storage | 4°C |
| Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
| UniProt Number | P11215 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
