Article No
155-76-387
Specifications
| NCBI Number | 929 |
| Application | FC |
| Article No | 155-76-387 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 61D3 |
| Clone Type | monoclonal |
| Concentration | batch dependent |
| Description | CD14 Antibody [61D3] (Violet-450) |
| Supplier | ProSci |
| Entrez Gene ID | 929 |
| Format | Liquid |
| Gene Symbol | CD14 |
| Isotype | IgG1 k |
| Notes | The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB. BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm. |
| Alias Names | CD14, CD14 |
| Previous Article No | 155-76-387-100 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 100 tests |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
| UniProt Number | P08571 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
