Article No
155-76-421
Specifications
| NCBI Number | 960; 12505 |
| Application | FC |
| Article No | 155-76-421 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | IM7 |
| Clone Type | monoclonal |
| Concentration | batch dependent |
| Conjugation | PerCP/Cy5.5 |
| Description | CD44 Antibody [IM7] (PerCP-Cy5.5) |
| Supplier | ProSci |
| Entrez Gene ID | 12505,960 |
| Format | Liquid |
| Gene Symbol | Cd44, CD44 |
| Isotype | IgG2b k |
| Notes | The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes. |
| Alias Names | IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III, Ly-24, Pgp-1, HERMES, AU023126, AW121933, AW146109, CD44 |
| Previous Article No | 155-76-421-0.1 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology, Stem Cell |
| Shipping Information | BLUE ICE |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | human, mouse |
| Storage | 4°C |
| Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
| UniProt Number | P15379, P16070 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
