Article No
155-90-312
NCBI Number | 356 |
Accession Number | P48023 |
Article No | 155-90-312 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Concentration | 0.1 mg/ml |
Description | FasL Soluble Recombinant Protein |
Supplier | ProSci |
Entrez Gene ID | 11546,356 |
Format | Lyophilized |
Gene Symbol | FASLG, Parp2 |
Notes | Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development. |
Alias Names | APO-1L, CD95L, CD178, TNFSF6, Fas Ligand |
Previous Article No | 155-90-312-10 |
Product Type | Proteins & Peptides |
Protocol | This recombinant proteins is for research use only. |
Purity | >95% |
Research area | Cell Death |
Sequence | Human FasL (aa 139-281) is fused at the N-terminus to the Fc portion of human IgG1. |
Shipping Information | RT |
Size | 10 ug |
Storage | -20°C |
Substrate / Buffer | Contains PBS. Reconstitute with 100 μl sterile water. |
Technical Specifications | Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml. |
UniProt Number | O88554, P48023 |
Product Page Updated | 2024-01-03T13:34:25.701Z |