Article No
155-90-342
PARP-3 [ARTD3] high purity Recombinant Protein
PARP-3 [ARTD3] high purity Recombinant Protein
Proteins & Peptides
Specifications
| NCBI Number | 10039 |
| Accession Number | Q9Y6F1 |
| Article No | 155-90-342 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Concentration | Lot dependent (0.2-1mg/ml) |
| Description | PARP-3 [ARTD3] high purity Recombinant Protein |
| Supplier | ProSci |
| Entrez Gene ID | 10039,6367 |
| Format | Liquid |
| Gene Symbol | CCL22, PARP3 |
| Notes | PARP-3 [ARTD3] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing. |
| Alias Names | Poly(ADP-ribose) Polymerase 3, ADP-ribosyltransferase Diphtheria Toxin-like 3, NAD(+) ADP-ribosyltransferase 3 |
| Previous Article No | 155-90-342-10 |
| Product Type | Proteins & Peptides |
| Protocol | This recombinant proteins is for research use only. |
| Purity | >98% |
| Research area | Cell Death |
| Sequence | Human full-length PARP-3 [ARTD3] is fused to a HA-tag and a His-tag. |
| Shipping Information | DRY ICE |
| Size | 10 ug |
| Storage | Stable for at least 6 months after receipt when stored at -80°C. |
| Substrate / Buffer | In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. |
| Technical Specifications | >10U/mg protein (only monoADP-ribosyl transferase activity). |
| UniProt Number | O00626, Q9Y6F1 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
