Article No
155-92-146
Death Receptor 6 Recombinant Protein
Death Receptor 6 Recombinant Protein
Proteins & Peptides
Specifications
| MW | 61.7 kD |
| NCBI Number | 27242 |
| Accession Number | O75509 |
| Article No | 155-92-146 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Description | Death Receptor 6 Recombinant Protein |
| Supplier | ProSci |
| Entrez Gene ID | 27242 |
| Format | Lyophilized |
| Gene Symbol | TNFRSF21 |
| Notes | Tumor Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation. In addition, DR6 binds with N-APP, which is released by the deprivation of Trophic-factor. It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). DR6 is also expressed on the tumor cell lines and can be induced by TNF- alpha. |
| Alias Names | Tumor Necrosis Factor Receptor Superfamily Member 21, Death Receptor 6, CD358, TNFRSF21, DR6, UNQ437/PRO868 |
| Previous Article No | 155-92-146-0.05 |
| Product Type | Proteins & Peptides |
| Protocol | This recombinant protein can be used for biological assays. For research use only. |
| Purity | >95% |
| Research area | Cell Death |
| Sequence | Gln42-Leu350 |
| Shipping Information | RT |
| Size | 0.05 mg |
| Storage | -20°C, 4°C, RT |
| Substrate / Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. |
| UniProt Number | O75509 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
