Article No
155-92-374
MW | 44.7 kD |
NCBI Number | 21942 |
Accession Number | P20334 |
Article No | 155-92-374 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Description | 4-1BB Recombinant Protein |
Supplier | ProSci |
Entrez Gene ID | 21942 |
Format | Liquid |
Gene Symbol | Tnfrsf9 |
Notes | Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice. |
Alias Names | Secreted CD137 antigen ,Tumor necrosis factor receptor superfamily member 9 ,Tnfrsf9, TNFRSF9, CD137 |
Previous Article No | 155-92-374-0.05 |
Product Type | Proteins & Peptides |
Protocol | This recombinant protein can be used for biological assays. For research use only. |
Purity | >95% |
Sequence | Val24-Leu187 |
Shipping Information | DRY ICE |
Size | 0.05 mg |
Storage | -20°C |
Substrate / Buffer | Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. |
UniProt Number | P20334 |
Product Page Updated | 2024-01-03T13:34:25.701Z |