14-3-3 Beta

Article No	155-96-781-0.1
Product Type	Proteins & Peptides
Research Area	Cell Proliferation
Application	WB
Format	Lyophilized
Size	0.1 mg
Quantity

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Specifications

MW	55 kDa
Country Availability	DK, EE, FI, FO, GL, IS, LT, LV, NO, SE
Data Sheet Link	http://www.prosci-inc.com/pdf.php?sku=96-781
Description	14-3-3 Beta Recombinant Protein
Supplier	ProSci incorporated
Notes	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB) is also known as 14-3-3 protein beta, GW128, HS1. YWHAB belongs to the 14-3-3 family. YWHAB binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. YWHAB is negative regulator of osteogenesis. YWHAB blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.
Alias Names	YWHAB, KCIP-1, 14-3-3 beta, GW128, HS1
Purity	>95% as determined by SDS-PAGE.
References	Liu Y., et al., 2007, Mol. Endocrinol. 21:3050-3061.
Size	0.1
Source / Host	bacteria
Species Reactivity	human
Storage	Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Substrate / Buffer	50 mM Tris, 150 mM NaCl, pH 7.4
Product Page Updated	2019-01-08T16:04:55.621Z

Shipping info

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