Article No
182-HM2120-20UG
CD59, Human, mAb MEM-43 – 20 µg
CD59, Human, mAb MEM-43 – 20 µg
Antibodies Primary
Specifications
| Application | FC, FS, IP, WB |
| Article No | 182-HM2120-20UG |
| Country Availability | SE, FI, DK, NO, EE, LV, LT |
| Clone | MEM-43 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | CD59, Human, mAb MEM-43 – 20 µg |
| Supplier | Hycult biotechnology |
| Format | Sterile 0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS and 0.1% bovine serum albumin with low endotoxin level. |
| Isotype | IgG2a |
| Notes | The antibody is the prototypic antibody for the CD59 determinant, a PI-linked glycoprotein of 18-25 kDa, which is broadly expressed on most types of cells. The antigen is the major complement-protecting molecule of human cells. It is expressed on all leukocytes, erythrocytes and most other cell types. Binding of this antibody inhibits the complement-protecting activity of CD59. CD59 is one of the complement regulatory membrane proteins that is missing in Paroxysmal Nocturnal Haemoglobinuria (PNH). Anti CD59 reagents may be useful in the differential diagnosis of PNH type II and PNH type I. Recently a role for CD59 in LPS signal transduction has been reported in keratinocytes. The antibody reacts with well defined epitope (W40, R-53) on CD59 molecule. |
| Previous Article No | 182-HM2120-20UG, HM2120-20UG |
| Product Type | Antibodies Primary |
| Research area | Immunology |
| Shipping Information | Room Temperature |
| Size | 20 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Product should be stored at 4°C. Under recommended storage conditions, product is stable for one year. |
| Substrate / Buffer | Sterile 0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS and 0.1% bovine serum albumin with low endotoxin level. |
| Product Page Updated | 2024-04-05T09:42:44.568Z |
