Article No
30-1635-0.1
CD86
Anti-CD86 Monoclonal Antibody (Clone:GL-1)-Low Endotoxin
Antibodies Primary
Specifications
| Application | FA, FC, ICC, IHC, IP |
| Article No | 30-1635-0.1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | GL-1 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-CD86 Monoclonal Antibody (Clone:GL-1)-Low Endotoxin |
| Supplier | Abeomics |
| Entrez Gene ID | 12524 |
| Gene Symbol | Cd86 |
| Immunogen | LPS-activated CBA/Cs mouse splenic B cells |
| Isotype | IgG2a |
| Notes | CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response. |
| Alias Names | FCAR||CD89, IgA Fc receptor |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry Recommended dilution: 2 µg/ml Positive control:mouse splenocytes Immunoprecipitation Immunohistochemistry (frozen sections) Immunocytochemistry Functional Application Blocking |
| Purification | Protein G Purified |
| Shipping Information | Blue Ice |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 4°C |
| UniProt Number | P42082 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
