Article No
30-2105-100
CD200
Anti-CD200 Monoclonal Antibody (Clone:OX-104)-FITC Conjugated
Antibodies Primary
Specifications
| Application | FA, FC, IHC |
| Article No | 30-2105-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | OX-104 |
| Clone Type | monoclonal |
| Conjugation | FITC |
| Description | Anti-CD200 Monoclonal Antibody (Clone:OX-104)-FITC Conjugated |
| Supplier | Abeomics |
| Entrez Gene ID | 4345 |
| Gene Symbol | CD200 |
| Immunogen | Human CD200 |
| Isotype | IgG1 |
| Notes | CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization. |
| Alias Names | OX-2 membrane glycoprotein, MOX1, MOX2 |
| Product Type | Antibodies Primary |
| Shipping Information | Blue Ice |
| Size | 100 Tests |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P41217 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
