Article No
30-2311-0.1
CD161
Anti-CD161 Monoclonal Antibody (Clone:10/78)-PE Conjugated
Antibodies Primary
Specifications
| Application | FC |
| Article No | 30-2311-0.1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 10/78 |
| Clone Type | monoclonal |
| Conjugation | PE |
| Description | Anti-CD161 Monoclonal Antibody (Clone:10/78)-PE Conjugated |
| Supplier | Abeomics |
| Entrez Gene ID | 362443 |
| Gene Symbol | Klrb1a |
| Immunogen | Splenic cells purified from the LEW rat |
| Isotype | IgG1 |
| Notes | CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on rat NK cells, subset of T cells, dendritic cells, and activated monocytes. Although human CD161 is expressed as one isoform, the rat CD161 has three isoforms, referred to as CD161a, b, and c. These proteins contain C-terminal C-type lectin extracellular domain, a transmembrane domain, and N-terminal intracellular domain, which contains ITIM motif, such as CD161b, and displays inhibitory function, or does not contain ITIM motif, thus also not the inhibitory function, such as CD161a. |
| Alias Names | T-cell surface antigen CD2, Erythrocyte receptor, T-cell surface antigen T11/Leu-5 |
| Product Type | Antibodies Primary |
| Shipping Information | Blue Ice |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | rat |
| Storage | 4°C |
| UniProt Number | P27471 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
