Article No
303-AHIgG-AGA-5
Application | IHC |
Article No | 303-AHIgG-AGA-5 |
Country Availability | SE, FI, DK, NO, EE, LV, LT |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | Chicken anti Human IgG (H/L), conjugated with Agarose |
Supplier | Exalpha Biologicals |
Format | Gel |
Immunogen | Recombinant human Calretinin |
Notes | The antibody is suitable for the detection of Calretinin in neurons and may be used as an aid in differential diagnosis of pleura-mesothelioma. This marker is frequently expressed in epitheloid mesothelioma, while occasionally it turns positive in sarcomatous mesothelioma and carcinoma. It was found to be negative in sarcoma (2,3) and in 90% of adenocarcinoma. Calretinin is a Calcium-binding protein related to Calmodulin and Calbindin. It is found in groups of neurons of the brain cortex, in the retina and in the spinal cord (1). More recent studies show that it is a suitable marker for mesothelioma of the lung (2, 3, 4, 5). Calretinin. |
Product Type | Antibodies Secondary |
Protocol | (liquid conc.) 1:40-1:50 |
Purification | Egg-yolk derived IgY Affinity Purified |
Size | 5.0 ml bed volume |
Source / Host | chicken |
Species Reactivity | human |
Storage | Product should be stored at 4-8ºC. DO NOT FREEZE |
Substrate / Buffer | Phosphate buffered saline‚ pH 7.2 with 0.075% sodium azide |
Technical Specifications | The specific activity of the anti-HIgG-agarose was determined. For this lot, 1.0 mg human IgG bound per ml agarose. |
UniProt Number | P22676 (CALB2_HUMAN) |
Product Page Updated | 2023-12-29T14:25:47.027Z |