Article No
32-20202-10
Article No | 32-20202-10 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Description | Animal-Free Recombinant Human IL-1Beta |
Supplier | Abeomics |
Notes | Source:E.coli IL-1Beta is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1Alpha and IL-1Beta bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1Beta is a secreted cytokine, IL-1Alpha is predominantly a cell-associated cytokine. Recombinant Human IL-1Beta is a 17.3 kDa protein containing 153 amino acid residues. |
Product Type | Proteins & Peptides |
Protocol | Determined by its ability to stimulate the proliferation of mouse D10S cells. The expected ED50 is = 1 x 109units/mg. |
Purification | Purity: >= 98% by SDS-PAGE gel and HPLC analyses. |
Sequence | APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS |
Size | 10 µg |
Substrate / Buffer | This recombinant protein is supplied in lyophilized form. |
Product Page Updated | 2024-05-08T07:23:11.080Z |