Article No
32-7375-10
Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 (C-6His)
Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 (C-6His)
Proteins & Peptides
Specifications
| Article No | 32-7375-10 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Description | Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 (C-6His) |
| Supplier | Abeomics |
| Entrez Gene ID | 59272 |
| Gene Symbol | ACE2 |
| Notes | Source: Human Cells. MW :84.63kD. Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a 6His tag at the C-terminus. Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don't inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function. |
| Product Type | Proteins & Peptides |
| Protocol | Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test. Biological Activity : Specific Activity is greater than 800 pmol/min/µg. |
| Sequence | Gln18-Ser740: QSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVSVDHHHHHH |
| Shipping Information | DRY ICE |
| Size | 10 µg |
| Storage | -20°C |
| Substrate / Buffer | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, 0.1mM ZnCl2, 10% Glycerol, pH 7.5. |
| UniProt Number | Q9BYF1 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
