Article No
36-1639-100
Bcl-2 (Apoptosis & Follicular Lymphoma Marker)
Monoclonal Antibody to Bcl-2 (Apoptosis & Follicular Lymphoma Marker)(Clone : 100/D5)
Antibodies Primary
Specifications
| Application | FC, IF, IHC, WB |
| Article No | 36-1639-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 100/D5 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to Bcl-2 (Apoptosis & Follicular Lymphoma Marker)(Clone : 100/D5) |
| Supplier | Abeomics |
| Entrez Gene ID | 596 |
| Gene Symbol | BCL2 |
| Immunogen | A synthetic peptide, aa41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein. |
| Isotype | IgG1 k |
| Keywords | Antibodies, Cancer Marker, Bcl-2 (Apoptosis & Follicular Lymphoma Marker), BCL2, 596, P10415, BCL2, 100/D5, A synthetic peptide, aa41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein., Monoclonal Antibody to Bcl-2 (Apoptosis & Follicular Lymphoma Marker)(Clone : 100/D5), Antibody to Bcl-2 (Apoptosis & Follicular Lymphoma Marker), Anti-Bcl-2 (Apoptosis & Follicular Lymphoma Marker) Antibody, Bcl-2 (Apoptosis & Follicular Lymphoma Marker) Antibody |
| Notes | This antibody recognizes a protein of 25-26kDa, identified as the bcl-2 a oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 a oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 a protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative. |
| Alias Names | BCL2 |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Western Blot (1-2ug/ml); ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes) |
| Purification | Affinity Purified |
| Shipping Information | BLUE ICE |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | P10415 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
