Article No
36-2945-20
Plakophilin-1 (PKP1)
Anti-Plakophilin-1 (PKP1) Monoclonal Antibody(Clone: 10B2)
Antibodies Primary
Specifications
| Application | FC, IF, WB |
| Article No | 36-2945-20 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 10B2 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-Plakophilin-1 (PKP1) Monoclonal Antibody(Clone: 10B2) |
| Supplier | Abeomics |
| Entrez Gene ID | 5317 |
| Gene Symbol | PKP1 |
| Immunogen | N-terminus of human Plakophilin-1 protein |
| Isotype | IgG1 k |
| Notes | Recognizes a protein of 75kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. |
| Alias Names | B6P; Band 6 protein; PKP1; Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome) |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Western Blot (1-2ug/ml) |
| Shipping Information | Blue Ice |
| Size | 20 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Storage | 4°C, -80°C |
| Substrate / Buffer | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| UniProt Number | Q13835 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
