Article No
36-3456-20
Application | FA, FC, IF |
Article No | 36-3456-20 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 100-1A5 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | Anti-CD1b (T-Cell Surface Glycoprotein) Monoclonal Antibody(Clone: 100-1A5) |
Supplier | Abeomics |
Entrez Gene ID | 910 |
Gene Symbol | CD1B |
Immunogen | Stimulated human leukocytes |
Isotype | IgM k |
Notes | The Mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV; Code T015). It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. |
Alias Names | A1 domain; CD1B; Cortical thymocyte antigen CD1B; hTa1 thymocyte antigen; Ly38; T cell surface glycoprotein CD1b; T6/Leu6 |
Product Type | Antibodies Primary |
Protocol | Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Functional Studies (Order Ab without BSA & Azide) |
Shipping Information | Blue Ice |
Size | 20 µg |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C, -80°C |
Substrate / Buffer | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
UniProt Number | P29016 |
Product Page Updated | 2024-02-06T07:35:53.072Z |