Article No
A68314-050
CHD1 Polyclonal Antibody
CHD1 Polyclonal Antibody
Antibodies Primary
Specifications
| Application | ELISA, IHC, ChIP |
| Article No | A68314-050 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, GL |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | CHD1 Polyclonal Antibody |
| Supplier | Epigentek |
| Format | Affinity Purified |
| Immunogen | Recombinant Human Chromodomain-helicase-DNA-binding protein 1 protein (1501-1710AA) |
| Isotype | IgG |
| Keywords | Chromatin Remodeling |
| Notes | ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity. Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells. _x000D_ |
| Alias Names | CHD-1, ATP-dependent helicase CHD1, CHD1 |
| Product Type | Antibodies Primary |
| Purity | Affinity Purified |
| Research area | Epigenetics |
| Size | 50 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze. |
| Substrate / Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| UniProt Number | O14646 |
| Product Page Updated | 2024-02-13T10:42:34.821Z |
