Article No
AAT-USCVUM-50
HTRA2/OMI (S306A)
Human HTRA2/OMI (S306A) antibody
Antibodies Primary
Specifications
| NCBI Number | NP_037379 |
| Accession Number | NP_037379 |
| Application | ELISA, WB |
| Article No | AAT-USCVUM-50 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | 1B3 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Human HTRA2/OMI (S306A) antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 27429 |
| Gene Symbol | HTRA2 |
| Immunogen | Recombinant human HtrA2/Omi (134-458aa) purified from E. coli |
| Isotype | IgG1 k |
| Notes | HtrA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP) -binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death. |
| Alias Names | High temperature requirement protein A2, HTRA2, OMI, PRSS25, HtrA2/Omi, EC 3.4.21.108, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine proteinase OMI, Serine protease 25, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2 |
| Product Type | Antibodies Primary |
| Protocol | The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000. |
| Purification | Protein G Purified |
| Size | 50ul |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| Substrate / Buffer | Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol. |
| UniProt Number | O43464 |
| Product Page Updated | 2024-04-17T08:35:56.016Z |
